| | Statistic | FOR | OPP |
| Total Yards per Game | 346.5 | 308.1 |
| Rushing YDS per ATT | 4.2 | 4.0 |
| Passing YDS per ATT | 6.4 | 7.2 |
| Passing Comp % | 0.659 | 0.652 |
| Total YDS per Play | 5.3 | 5.7 |
| Total YDS per Point | 15.8 | 15.9 |
|
| Injury |
| [RB] Laurence Maroney IR - Shoulder - 10/17/08 |
| (!) [QB] Tom Brady IR - Knee - 09/07/08 |
| [DE] Ty Warren missed last game, "?". - Groin - 11/13/08 |
| [S] Rodney Harrison IR - Knee - 10/21/08 |
| [C] Dan Koppen is "?". - Undisclosed - 11/14/08 |
| [RB] LaMont Jordan missed last game, %27?%27 - Calf - 11/13/08 |
| [LB] Eric Alexander missed last game, %27?%27 - Hamstring - 11/13/08 |
| [DB] Raymond Ventrone injured last game, %27?%27 - Concussion - 11/13/08 |
| [S] Tank Williams IR. - Knee - 08/09/08 |
| [LB] Adalius Thomas is out indefinitely - Arm - 11/10/08 |
| [LB] Shawn Crable IR - Shin - 11/05/08 |
| [CB] Terence Wheatley IR - Wrist - 11/17/08 |
| [LB] Jerod Mayo is "?". - Undisclosed - 11/14/08 |